PharmacyLesson 1 of 2 in the course Routes of drug administration

Drug Administration Routes: Classification, Delivery, and Selection

5 flashcards · 5 quiz questions · 5 match pairs · 5 fill-in sentences · English

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Summary

A route of administration is the way a drug or other substance enters the body. Understanding routes helps explain how a medicine reaches its target and why the same substance may act differently when delivered in different ways.

A route of administration (ROA) describes the way a drug, fluid, poison, or other substance is introduced into the body. Routes are commonly classified by the application location—the place where the substance is applied or introduced.

All flashcards

What does pharmacokinetics study?
Drug uptake, distribution, and elimination.
What does enteral administration mean?
Delivery by way of the gastrointestinal tract.
Why are some tablets enteric-coated?
To delay dissolution until the intestine, which can protect a drug from stomach acid or reduce stomach irritation.
How can absorption from the distal rectum affect a drug’s bioavailability?
It may partially avoid the liver’s first-pass effect, increasing bioavailability for some drugs compared with oral administration.
Why are many protein medicines not taken orally?
They are digested in the stomach and may become ineffective when swallowed.

Quiz questions

  1. What does parenteral administration mean?Answer: Administration by a route other than the gastrointestinal tract.
  2. Which injection route delivers a medicine into muscle tissue?Answer: Intramuscular
  3. Why does intravenous administration provide very high bioavailability?Answer: It delivers the drug directly into the bloodstream.
  4. In inhaled drug delivery, where do particles sized 3–8 μm tend to deposit?Answer: Transitional lung regions, mainly by sedimentation.
  5. What is a potential benefit of delivering a drug close to its intended site of action?Answer: It can reduce systemic exposure and the risk of systemic side effects.

Based on the Wikipedia article Route of administration, licensed CC BY-SA 4.0. Adapted into a summary, flashcards and quizzes.

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